Publications

Journals

A novel apoptosis-inducing anti-PSGL-1 antibody for T cell-mediated diseases.

PublishedEur J Immunol. 2005 Jul;35(7):2239-49.
Author (s)Huang CC, Lu YF, Wen SN, Hsieh WC, Lin YC, Liu MR, Chiang E, Chang CN, Lin RH.
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Cross-linking of P-selectin glycoprotein ligand-1 induces death of activated T cells.

PublishedBlood. 2004 Nov 15;104(10):3233-42. Epub 2004 Jun 15.
Author (s)Chen SC, Huang CC, Chien CL, Jeng CJ, Su HT, Chiang E, Liu MR, Wu CH, Chang CN, Lin RH.
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Conference Abstracts

Checkpoint Regulator, Neihulizumab, as a Novel Therapy for Immunological Diseases

PublishedB & T Cell-Mediated Autoimmune Disease Drug Development
Author (s)Judy Chou
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Efficacy and Safety of Neihulizumab (AbGn-168H) in Patients with Active Psoriatic Arthritis: 24-week Results from a Phase II Open Label Study

PublishedAmerican College of Rheumatology (ACR)
Author (s)Stanley B. Cohen, Justus J. Fiechtner, Philip J. Mease, Jeffrey L. Kaine, Arthur Kavanaugh, Yi-Lin (Irene) Cheng, Claire Chou, Ting-Ying Cheng, I-Ming Cho, Shih-Yao Lin and Mark C. Genovese
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NEIHULIZUMAB (ABGN-168H) IN PATIENTS WITH STEROID-REFRACTORY ACUTE GRAFTVERSUS- HOST-DISEASE (SR-AGVHD): PRELIMINARY RESULTS OF A PHASE I STUDY

PublishedEuropean Hematology Association (EHA)
Author (s)Sameen Abedin, Mehdi Hamadani, Shernan G Holtan, Sarah Anand, Irene Cheng, Iming Cho, Ting-Ying Cheng, Shih-Yao Lin and Paul J Martin
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Phase II open label, single arm, multiple dose study of Neihulizumab , an anti CD162 (PSGL 1) antibody, in patients with moderate to severe active, anti TNFα and/or anti integrin refractory ulcerative colitis

PublishedDigestive Disease Week (DDW)
Author (s)David T. Rubin , Scott Lee , Lucky Flores , Gustavo Albizu Angulo , Ellen Scherl , Surinder Saini , Shipra Patel , Yi Lin (Irene) Cheng , Ting Ying (Hazel) Cheng , and Shih Yao Lin
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Phase Ia,first-in-human study of AbGn-107,a novel antibody-drug conjugate(ADC),in patients with gastric,colorectal,pancreatic,or biliary cancers

PublishedAmerican Society of Clinical Oncology (ASCO)
Author (s)Andrew H.Ko,Andrew L.Coveler,Benjamin L.Schlechter,Tanios S.Bekaii-Saab,Brian M.Wolpin,Jeffery W.Clark,Bruno Bockorny,Yi-Lin Cheng,Ting-Ying Cheng,Peter Langecker and Shih-Yao Lin
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