AltruBio

PRODUCT PIPELINE

• Product
  Indication

  • Preclinical
  • Phase I
  • Phase IIa
  • Phase IIb
  • Phase III
• Immunology Product - PSGL1:T-Cell Checkpoint Regulator Platform

• ALTB-168 Neihulizumab

  Psoriatic Arthritis

  • PRECLINICAL

  • PHASE I

  • PHASE IIA

  • PHASE IIB

  • PHASE III

  • MARKET

  Phase II Phase 2a Psoriatic Arthritis trial completed with proof of clinical efficacy achieved.

  Ulcerative Colitis

  • PRECLINICAL

  • PHASE I

  • PHASE IIA

  • PHASE IIB

  • PHASE III

  • MARKET

  Phase II Phase 2a anti-TNF α and/or anti-integrin refractory/intolerant Ulcerative Colitis trial completed with proof of clinical efficacy achieved; continued UC development planned with ALTB-268.

  Steroid Refractory Acute Graft Versus Host Disease

  • PRECLINICAL

  • PHASE I

  • PHASE IIA

  • PHASE IIB

  • PHASE III

  • MARKET

  Phase I Phase 1b multi-dose steroid refractory acute graft versus host disease trial ongoing

  Acute Graft Versus Host Disease

  • PRECLINICAL

  • PHASE I

  • PHASE IIA

  • PHASE IIB

  • PHASE III

  • MARKET

  Phase I Investigator sponsored Phase 1 front line acute graft versus host disease trial ongoing.

• ALTB-268

  Ulcerative Colitis

  • PRECLINICAL

  • PHASE I

  • PHASE IIA

  • PHASE IIB

  • PHASE III

  • MARKET

  Phase 1 Potency improved version of ALTB-168, Phase 1 trial in healthy volunteers.

  Solid Organ Transplantation

  • PRECLINICAL

  • PHASE I

  • PHASE IIA

  • PHASE IIB

  • PHASE III

  • MARKET

  Preclinical Renal Transplantation Non-Human Primate preclinical studies ongoing.